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Diabetes and Menopause

Menopause appears to be associated with a decrease in pancreatic insulin secretion as well as increased insulin resistance. These changes are thought to contribute to the increased risk for developing T2DM after menopause although it is not clear whether this is due to only to the postmenopausal lower estrogen status of with aging. However, two landmark studies in women’s health, the Heart and Estrogen/progestin Replacement Study (HERS) and the Women’s Health Initiative (WHI), both suggest that estrogen alone or combined estrogen-progesterone therapy reduces the incidence of new-onset diabetes.

The connection between estrogen and insulin resistance and T2DM is further strengthened by a meta-analysis quantifying the effects of hormone therapy on metabolic syndrome in postmenopausal women. This meta-analysis found that hormone therapy in peri and post menopausal women improved insulin resistance and fasting glucose in women with diabetes and improved insulin resistance, lipid levels, blood pressure and abdominal obesity in women without diabetes. These 3 studies strongly suggest that normal physiologic low estrogen levels that occur in menopause do indeed influence the development of insulin resistance, metabolic syndrome and T2DM in peri and postmenopausal women.

The following are some examples of “natural ingredients” that can be used to balance insulin sensitivity:

1. Berberine has been shown to significantly lower fasting glucose, hemoglobin A1c, triglycerides and insulin levels in patients with T2DM
2. Bitter melon’s ability to lower blood sugar has been demonstrated in both animal and human studies. The fruit has the ability to increase the storage of glucose, decrease the body’s production of glucose, increase insulin production and decrease insulin resistance
3. Cinnamon bark contains cinnamaldehyde and polypheolic polymers that have been found to have glycemic and antioxidant effects that should be considered in MS and T2DM
4. The blueberry leaf contains phenolic compounds, such as chlorogenic acid and caffeic acids that are involved in optimizing glucose absorption and glucose metabolisms. Blueberries themselves, have also been studied for their impact on insulin sensitivity

In conclusion, it’s important to note that treating hyperglycemia, insulin resistance, or T2DM is necessary, but also that the underlying roots may be buried in various diseases states. Determining the root of origin may be buried in treating hypertension, dyslipidemia, endothelial dysfunction, vascular inflammation and obesity. Uncovering an imbalance in hormones that may be due to menopause, stress, lifestyle or diet is the 1st step in revealing the path to healing T2DM or insulin resistance as well.

For more information please contact Dr Nirvana at www.DrNirvana.com

Source by Dr Nirvana

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