HomeVideoPathophysiology of Diabetes Ketoacidosis (DKA)

Pathophysiology of Diabetes Ketoacidosis (DKA)

In this video I have the pathophysiology of diabetes ketpacidosis seen primarily in type 1 diabetes mellitus. Absolute deficiency of insulin leads to increase in glucagon and decreased peripheral utilization of glucose leading to increased blood glucose level. Increased glucagon along with catecholamines and cortisol leads to increased gluconeogenesis thereby outpouring of glucose from liver into blood which increases blood glucose level. Increased lipolysis leads to increased free fatty acids leading to increased generation of ketone bodies. Increased ketone bodies like acetoacetate and beta-hydroxybutyrate in the blood lead to decrease in blood pH leading to metabolic acidosis.

You Can Subscribe to my Channel for REGULAR UPDATES by clicking on SUBSCRIBE button above!

You can follow me on my BLOG by clicking the link below

You can follow my Facebook page Biochemistry Made Easy by Dr Prakash Mungli, MD by clicking the link below. Here I post USMLE step-1 style MCQs and you can participate in discussion.



Previous post
Community-based program helps women control and cope with diabetes
Next post
2016 Dancing for Diabetes THANK YOU!

Leave a Reply

Be the First to Comment!

Notify of